Sex differences in acute myocardial infarction: clinical characteristics, management practices, and outcomes for patients in a large tertiary hospital from Palestine

Authors

Yunis Daralammouri, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine. & Department of Cardiology, An-Najah National University Hospital, Nablus 44839, PalestineFollow
Mohammed Jabri, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Osayd Mosleh, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Yazan AbdelAziz, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Murad Azamtta, Department of Cardiology, An-Najah National University Hospital, Nablus 44839, Palestine
Adham Abu Taha, Department of Pathology, An-Najah National University Hospital, Nablus 44839, Palestine. & Department of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa’ed Zyoud, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine. & Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine. & Clinical Research Center, An-Najah National University Hospital, Nablus 44839, PalestineFollow

Abstract

Several studies have shown gender variations in acute coronary syndrome's clinical presentation, diagnosis, therapy, and outcomes. Both immediate and long-term outcomes were worse for women with the acute coronary syndrome than men. This study investigates the influence of sex differences on the clinical presentations, treatment approaches, and patient outcomes of acute myocardial infarction at a large tertiary hospital in Palestine. A retrospective cohort study included all patients with acute myocardial infarction who presented to An-Najah National University Hospital from January 2018 to December 2020. Of the 422 patients in this study, 96 (22.7%) were women. Compared to men, women were older (p <0.001) and had significantly higher rates of diabetes mellitus (p <0.001) and hypertension (p <0.001). Additionally, women had greater chances of complaining of atypical cardiac chest pain (p = 0.012). Furthermore, non-ST segment elevation myocardial infarction was more prevalent among women (p = 0.017). Regarding the hospital course, the median number of stents was statistically significant in men (p = 0.029), but women had significantly higher in-hospital mortality (p = 0.013) and a higher rate of blood transfusion (p = 0.026). Myocardial infarction presents differently in males and women. Women were older, had more comorbid conditions than men, had atypical presentations, and had higher in-hospital mortality rates. As a result, while evaluating and treating patients suspected of having a myocardial infarction, healthcare practitioners must account for these discrepancies to reduce the mortality rate among women.

Digital Object Identifier (DOI)

10.59049/2790-0231.1257

Recommended Citation

Daralammouri, Yunis; Jabri, Mohammed; Mosleh, Osayd; AbdelAziz, Yazan; Azamtta, Murad; Abu Taha, Adham; and Zyoud, Sa’ed (2023) "Sex differences in acute myocardial infarction: clinical characteristics, management practices, and outcomes for patients in a large tertiary hospital from Palestine," Palestinian Medical and Pharmaceutical Journal: Vol. 8 : Iss. 3 , Article 15.
Available at: https://doi.org/10.59049/2790-0231.1257